Page. _Load(Object sender, EventArgs e) in D:\SaffronMedia\TFS Applications\Pharmabiz\Pharmabiz\Pharmabiz\:140 Phoenix WinNonlin’s advanced reporting capabilities are very useful when compiling stand-alone PK reports, facilitating rapid illustration of PK data through workflows and templates however, when results are integrated into a large CSR, it is often preferable to generate TLFs in SAS for consistency with the remainder of the clinical report (e.g. Information regarding the origin and location of the exception can be identified using the exception stack trace below. Please review the stack trace for more information about the error and where it originated in the code.Įxception Details: System.FormatException: Input string was not in a correct format.Īn unhandled exception was generated during the execution of the current web request. Pharmacokinetics (from Ancient Greek pharmakon 'drug' and kinetikos 'moving, putting in motion' see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. Objectives The video gets you started with Phoenix WinNonlin 8. It is a secondary parameter, which can be derived from CL and V Rate of elimination CLC AUC. Clinically interesting because intuitive, used to calculate when steady state is reached. Description: An unhandled exception occurred during the execution of the current web request. Certara University offers many other courses to expand your theoretical and practical knowledge of PK/PD analysis using the Phoenix software. Relationship of PK parameters ( ) CL ln 2 V t 2 1 The elimination half-life is defined as the time for the drug concentration to reach half of its value. Input string was not in a correct format. (Princeton, NJ)) using actual sampling times. Input string was not in a correct format. Pharmacokinetic parameters will be calculated by Nuventra using Phoenix® WinNonlin® 6.3 or later (Certara USA, Inc.